Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos |
| Phenotype | phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2 |
| Enrichment Score (ES) | -0.7200359 |
| Normalized Enrichment Score (NES) | -1.7075472 |
| Nominal p-value | 0.001992032 |
| FDR q-value | 0.13072419 |
| FWER p-Value | 0.685 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | DKK1 | 1420360_at 1458232_at | 2478 | 0.512 | -0.0828 | No | ||
| 2 | PPP2R5D | 1450560_a_at | 2644 | 0.481 | -0.0620 | No | ||
| 3 | DKK2 | 1420512_at | 5272 | 0.240 | -0.1677 | No | ||
| 4 | FZD1 | 1422985_at 1437284_at | 5631 | 0.226 | -0.1707 | No | ||
| 5 | CTNNB1 | 1420811_a_at 1430533_a_at 1450008_a_at | 7984 | 0.149 | -0.2692 | No | ||
| 6 | PITX2 | 1424797_a_at 1450482_a_at | 10125 | 0.097 | -0.3611 | No | ||
| 7 | WNT1 | 1425377_at | 13758 | 0.008 | -0.5264 | No | ||
| 8 | WIF1 | 1425425_a_at | 14068 | -0.000 | -0.5405 | No | ||
| 9 | PROC | 1418845_at 1444979_at | 14212 | -0.004 | -0.5467 | No | ||
| 10 | LRP6 | 1451022_at | 15352 | -0.043 | -0.5962 | No | ||
| 11 | NKD2 | 1419465_at 1419466_at | 15527 | -0.049 | -0.6012 | No | ||
| 12 | DVL1 | 1437301_a_at 1450978_at | 17620 | -0.192 | -0.6853 | No | ||
| 13 | AXIN1 | 1426966_at 1426967_at 1441029_at | 17643 | -0.197 | -0.6747 | No | ||
| 14 | LDB1 | 1452024_a_at | 17694 | -0.200 | -0.6652 | No | ||
| 15 | HDAC1 | 1448246_at | 18588 | -0.320 | -0.6870 | No | ||
| 16 | TRRAP | 1416532_at | 19312 | -0.466 | -0.6926 | Yes | ||
| 17 | FRAT1 | 1449814_at | 19585 | -0.533 | -0.6735 | Yes | ||
| 18 | LEF1 | 1421299_a_at 1436398_at 1440760_at | 19824 | -0.603 | -0.6488 | Yes | ||
| 19 | CSNK2A1 | 1419034_at 1419035_s_at 1419036_at 1419037_at 1419038_a_at 1453427_at | 21003 | -1.246 | -0.6290 | Yes | ||
| 20 | EP300 | 1434765_at | 21052 | -1.301 | -0.5545 | Yes | ||
| 21 | GSK3B | 1434439_at 1437001_at 1439931_at 1439949_at 1451020_at 1454958_at | 21817 | -3.254 | -0.3973 | Yes | ||
| 22 | CCND2 | 1416122_at 1416123_at 1416124_at 1430127_a_at 1434745_at 1448229_s_at 1455956_x_at | 21828 | -3.314 | -0.2021 | Yes | ||
| 23 | CREBBP | 1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at | 21856 | -3.508 | 0.0037 | Yes |
